<p>The Clostridium neurotoxin family is composed of tetanus neurotoxin and seven serotypes of botulinum neurotoxin. The structure of the botulinum neurotoxin reveals a four domain protein. The N-terminal catalytic domain (<db_xref db="INTERPRO" dbkey="IPR000395"/>), the central translocation domain and two receptor binding domains [<cite idref="PUB00016466"/>]. This domain is the N-terminal receptor binding domain, which is comprised of two seven-stranded beta-sheets sandwiched together to form a jelly role motif [<cite idref="PUB00016466"/>]. The role of this domain in receptor binding appears to be indirect. </p> Clostridium neurotoxin, receptor binding N-terminal